David Rand awarded EPSRC Senior Fellowship
David Rand has been awarded a 5 year EPSRC Senior Fellowship in
To predict and preventing diseases such as cancer, diabetes and AIDS we
need to do more than identify the components that make up the machinery
of cells and tissues. We must also understand how these components
interact to produce normal and pathological behaviour. Since the
interactions between genes, transcripts, proteins, metabolites and cells
are complex and dynamics, mathematical modelling and analysis will be
needed for their understanding. Moreover, there is a rapidly growing
number of powerful technologies that probe gene expression and the
abundance and spatial distribution of metabolites and proteins. These
produce huge amounts of data and require the development of new
mathematical and statistical methods. This and the associated
experimental design problems pose considerable mathematical and
statistical challenges. This work will be developed in a number of
biological areas chosen with the expectation that results obtained for
these are likely to be generalisable. These include circadian clocks,
photoperiodism, immunology of T cells, plant development (flowering),
the control of apoptosis (cell suicide) and replication, and bacterial
signalling. The research involves extensive collaboration with
experimental groups and will be carried out in a multidisciplinary
context involving mathematical and physical scientists as well as
biologists and clinicians.
